NIKE foundation invests in marginalized adolescent girls as the untapped economic opportunities. Research shows that a key to combating poverty on a global scale is protecting, educating and investing in girls in developing regions, which will in turn strengthen communities as a whole. Many studies show that women in developing countries tend to invest more of their earnings into their family's well-being than men.

NIKE Foundation's Girls Effect Accelerator supports socially conscious revenue-generating enterprises that are positioned to benefit millions of girls living in poverty. The Girl Effect Accelerator, funded by Nike Foundation, includes 1) the provision of mentorship programs; 2) the arrangement of meetings with investors and business leaders, and 3) the establishment of strategic financing models such as revolving funds. Projects supported include mobile banking & mobile education as well as health and education projects, all aim at increasing girls access to education, prevent early marriage and teen pregnancy, stop female genital mutilation, economic empowerment, and enabling women to claim the right to inheritance and own land.

Similar to the Accelerator programs are Incubation programs. Nahdet Al Mahrousa, a local Egyptian NGO, has started its incubation program which aims to turn early-stage social initiatives and ideas into successful social enterprises. The incubation program provides 1) capacity building through training courses; 2) technical support through legal and business consultations; 3) networking; and 4) sharing working office infrastructure. The incubation program has supported 30+ social enterprises to start and scale up their social-ideas in education, environment, employment generation and facilitation, etc.